Environmental or self-antigens and homotypic interactions set off BCR and Toll-like receptor (TLR) signaling, amplifying the reaction of CLL cells to other signals within the microenvironment and escalating the activation of anti-apoptotic and proliferation pathways. . intolerance). Ibrutinib is the current gold conventional therapy for people with relapsed/refractory condition, depen... https://orlandoz220sjx9.mybuzzblog.com/profile