There is a release of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors inside the dorsal horn to decrease afferent pain transmission and produce analgesia. Consequently, prescription drugs like clonidine that target alpha-two receptors can influence the transmission of soreness. Clonidine is a long-term medication. It https://irvingo592lrn9.actoblog.com/profile