Conolidine’s analgesic results stem from its conversation with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors in the central anxious system, conolidine modulates alternate molecular targets. A Science Advancements analyze uncovered that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By inf... https://marioeryeh.idblogz.com/38092938/the-best-side-of-alternative-natural-pain-relief-to-replace-traditional-painkillers